THE 5-SECOND TRICK FOR BOSENTAN

Ketoconazole Coadministration of bosentan 125 mg twice each day and ketoconazole, a strong CYP3A inhibitor, enhanced the plasma concentrations of bosentan by around 100% in typical volunteers. No dose adjustment of bosentan is essential, but amplified consequences of bosentan should be regarded as.Some critical Uncomfortable side effects which nece